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However, GBE supplementation controlled the inflammatory reaction and oxidative stress pathways by regulating sphingolipid, phospholipid and glyceride metabolism and ameliorated the structural damage by downregulating amino acid metabolism (downregulation of urea cycle) and decreasing oxidative stress (Wang et al., 2016)

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Unlike the dog, these enzymes will only increase modestly in cats, even in severe disease, and there is no glucocorticosteroid or drug induction of the enzymes to influence interpretation.14, 37 Thus increases in ALP in the adult cat represent a release of enzyme from the hepatobiliary tree and should be considered clinically important